Search results for " Diuretic treatment"

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Early urinary sodium trajectory and risk of adverse outcomes in acute heart failure and renal dysfunction.

2021

Introduction and objectives: Urinary sodium (UNa+) has emerged as a useful biomarker of poor clinical outcomes in acute heart failure (AHF). Here, we sought to evaluate: a) the usefulness of a single early determination of UNa+ for predicting adverse outcomes in patients with AHF and renal dysfunction, and b) whether the change in UNa+ at 24 hours (Delta UNa24 h) adds any additional prognostic information over baseline values. Methods: This is a post-hoc analysis of a multicenter, open-label, randomized clinical trial (IMPROVE-HF) (ClinicalTrials.gov NCT02643147) that randomized 160 patients with AHF and renal dysfunction on admission to a) the standard diuretic strategy, or b) a carbohydra…

medicine.medical_specialtyRenal failureTratamiento diuréticoAntígeno carbohidrato 125medicine.medical_treatmentRenal function030204 cardiovascular system & hematologyInsuficiencia cardiaca agudaGastroenterologylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawInterquartile rangeInternal medicineBiomarker-guided therapyEnsayo clínicoTerapia guiada por biomarcadoresClinical endpointHumansMedicineDiureticsAgedAged 80 and overHeart Failurebusiness.industryFallo renalSodiumAcute heart failureGeneral Medicinemedicine.diseaseClinical trialClinical trialAcute heart failure Antígeno carbohidrato 125 Biomarker-guided therapy Carbohydrate antigen 125 Clinical trial Diuretic treatment Ensayo clínico Fallo renal Insuficiencia cardiaca aguda Renal failure Terapia guiada por biomarcadores Tratamiento diuréticoCarbohydrate antigen 125Heart failureAcute DiseaseDiuretic treatmentBiomarker (medicine)Kidney DiseasesDiureticbusiness
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